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Cannabis, Blog

Types of CBD: Spectrums and Presentations

The CBD universe includes a variety of extracts, formulas, and presentations that can raise many questions, especially if you’re just starting out or want to better understand the differences between its different forms. Whether you’re just starting out and want to know where to go, or you’ve been using CBD for a while and are looking to clarify some questions, this article is designed for you. What is the difference between the types of CBD? What does that mean full spectrum or isolated? And what type of product best fits what you’re looking for? What types of spectrum does CBD have? One of the most important ways to differentiate types of CBD is by their “spectrum.” This term refers to the compounds that remain in the final formula after the hemp extraction process. This plant contains many more components than cannabidiol: there are terpenes, which are the molecules responsible for aroma; flavonoids, with antioxidant properties; and other lesser-known cannabinoids such as CBG or CBN. Depending on the process, an extract can retain all of these elements, just some, or just CBD. Full Spectrum CBD Full-spectrum CBD retains a large portion of the natural compounds present in the hemp plant. This includes secondary cannabinoids, terpenes, and a small amount of THC that always stays below the legal limit allowed (0.2% in Spain). This combination allows for what is known as the “entourage effect”, a hypothesis described by Ethan Russo (2011), which raises the possibility that the different components of hemp interact with each other to enhance its properties. Therefore, if you are interested in a richer experience closer to the original plant composition, this could be a good alternative. Broad Spectrum CBD Broad-spectrum CBD maintains many of hemp’s compounds, such as terpenes and secondary cannabinoids, but goes through an additional process that removes THC completely. This means that it is still a complex extract with a variety of plant elements, but without the presence of tetrahydrocannabinol. It is an especially useful option if you prefer not to worry about the implications of THC but value more complete formulas that are closer to the nature of the plant. CBD isolate or pure (CBD Isolate) CBD isolate is a very precise way to work with this cannabinoid. Through purification techniques, a compound is obtained that contains only cannabidiol, without traces of terpenes, flavonoids or other cannabinoids. This format is usually recommended if your priority is the purity of your CBD, or if you’re looking to avoid other plant compounds altogether. It is common in environments where greater control is required, such as when under certain medical treatments or for professional reasons. Types of CBD presentations In addition to the type of spectrum, you can also distinguish CBD by the formats in which it is available. The presentations vary not only in shape or size, but also in experience, form of application, and sensory profile. Here we show you the most common ones so that you can identify the one that best suits what you need. CBD flowers or buds CBD flowers, also known as buds, are the visible parts of the plant that are carefully harvested and dried to preserve its natural aroma, structure, and composition. They come from industrial hemp, with low THC content and a significant percentage of CBD. The interesting thing about this format is the variety: each flower can offer a different profile of aromas, nuances and textures. Some have citrus notes, others are more earthy or fruity. Mini Buds CBD are part of this category; They are smaller buds that share the same properties as the large ones, but they are a more accessible and economical option if you want to try different varieties. CBD Oils CBD oils are one of the most widely used and versatile presentations. They are prepared by mixing a cannabidiol extract with a vegetable carrier oil, such as coconut, olive, or hemp oil. This foundation allows the CBD to stabilize and be easy to apply. Oils can have different concentrations, from 3% to higher levels such as 30 or 40%. There are also versions that incorporate natural ingredients such as chamomile, vitamin D or cannabinoids such as CBG, which expands the possibilities of use. Did you know that CBD can also be used by animals? (Corsato Alvarenga et al., 2023) You will also find CBD oils for pets, with ingredients and concentrations suitable for their body. CBD Hash or Resins CBD hash is a solid, concentrated presentation that is obtained from hemp resin. Depending on the production method, its texture can range from creamy to drier or more compact. Techniques such as dry sieving or mechanical pressing are used to concentrate the active compounds. This type of product is valued for its intensity, both in aroma and plant density. Each variety of hash can have different nuances: from spicy and earthy notes to sweeter fragrances. Its handcrafted look and power make it appealing to those looking for a more concentrated experience. CBD cosmetics: creams, balms, and topicals In the field of body care, CBD has also found its place. Today you can find a wide range of cosmetics that include it as an active ingredient: moisturizers, lip balms, ointments or massage oils. These products are designed to be applied to the skin and usually combine cannabidiol with plant extracts such as aloe vera, shea butter or essential oils. While research is still ongoing, many integrate them into wellness routines because of their texture, potential calming effect, and versatility in topical use. How to choose the right type of CBD for you? Making a decision may seem difficult with so many options available, but it doesn’t have to be. The first thing we recommend is to think about your goals and what kind of experience you are looking for. Do you prefer a formula that is as natural as possible? Interested in avoiding THC altogether? Or do you value a precise option without other plant components? If you’re drawn to the idea of

Oil CBD, Blog

Types of CBD Oils

In the world of wellness, CBD oils have earned an important place. You may well have heard about them, even considering buying one, but they raise many questions: what makes them different from each other? Why do some oils contain more compounds than others? And how can you know which one best suits what you’re looking for? Throughout this article, we will explain how they differ according to their composition, what ingredients can accompany them and how they are also presented in different formulas. At Maionais we work with different alternatives, and we believe that understanding what you wear is an essential part of your well-being. What is a CBD oil? Before going into the types of oil, it is worth pausing for a moment to understand what this product is. When we talk about CBD oil, we are referring to a preparation that combines hemp extracts with a vegetable oil. Hemp is a variety of cannabis with very low levels of THC, which is the substance best known for its psychoactive effects. CBD, on the other hand, is a non-psychoactive cannabinoid that has attracted attention for its potential and safety profile. This extract is mixed with oils such as coconut, olive or hemp seed oil, which stabilise the formula and facilitate its application. Depending on how it has been made, an oil can retain different elements of the original hemp or focus only on cannabidiol. And it is precisely this choice that gives rise to the different types of oils that you will find on the market. Differences according to the spectrum of CBD oils One of the most common ways to classify CBD oils is according to their “spectrum.” This word refers to the set of compounds contained in each formula. Hemp doesn’t just provide CBD: it also contains other cannabinoids, terpenes (which are flavored molecules), and flavonoids (plant compounds with other potentially beneficial properties). Depending on the extraction and filtering process, some oils retain more of these elements, while others opt for a simpler formula. Full-spectrum oil This type of oil retains most of the compounds that are present in the hemp plant. In addition to CBD, it usually contains small amounts of other cannabinoids such as CBG or CBN, as well as natural terpenes and a very low amount of THC, always below 0.2%, which is the legal limit allowed. The interesting thing about this type of formula is that it relies on what some studies have called the “entourage effect”: a possible interaction between the different components of hemp that could amplify its properties together. Although its true scope is still being researched, many people value this type of extract for its chemical richness and for preserving the natural complexity of the plant. Broad-spectrum oil Very similar to the above, broad-spectrum oil also includes several hemp compounds, such as minor cannabinoids and terpenes. The main difference is that it goes through a purification process to completely remove THC. This makes it an option that is still complete in terms of plant variety, but without the presence of that particular cannabinoid. It’s considered a good alternative if you’re interested in a formula that’s close to natural, but prefer to avoid any traces of tetrahydrocannabinol. CBD Oil Isolate Isolate is the most refined form of cannabidiol oils. In this case, the formula contains exclusively CBD, without terpenes or other cannabinoids. To obtain it, cannabidiol is separated from the rest of the hemp compounds through specific purification processes. It is an option that some people choose because of its predictability and simplicity. It can be useful when you want to have full control over what you are using, especially in environments where strict regulations are applied or you are looking to avoid any interaction with other plant compounds. Additional Ingredients in CBD Oils Beyond the type of spectrum, there are also oils that incorporate complementary ingredients of natural origin. These formulas seek to offer a more diverse profile, depending on different needs or preferences. Some products include minor cannabinoids such as CBG or CBN, which are also being studied for their potential. Others add elements such as natural extracts, essential oils or vitamin D, known for their possible contributions to everyday well-being. In all cases, these are combinations that seek to expand the field of action of the oil. At Maionais we develop different versions that contemplate this type of variants, making sure to choose only natural ingredients and explain everything in our store, so that you can choose with the security of knowing exactly what each option contains. Which type of CBD oil to choose according to the spectrum? The main reason why many people pay attention to the type of spectrum in CBD oils is the so-called “entourage effect”. This expression refers to the possible synergy that occurs when several hemp compounds act together. Rather than looking at just cannabidiol, this look proposes that terpenes, minor cannabinoids, and other elements of the plant could interact with each other, amplifying or modulating their overall effect. In his 2011 review, researcher Ethan Russo suggested that this interaction between cannabinoids and terpenes could have a relevant impact on perceived benefits, as well as how some compounds are tolerated (Russo, 2011). For this reason, both full-spectrum and broad-spectrum oils are often chosen by those who want formulas that retain some of that chemical richness. By maintaining multiple plant compounds, these oils could better take advantage of that potential combined effect, compared to an oil that contains only CBD isolate. Now, that doesn’t mean that CBD isolate doesn’t have advantages. One of its main strengths is to offer a clean formula without other compounds present in hemp, which allows elements such as THC to be completely avoided. Plus, by working with only purified cannabidiol, you can have peace of mind knowing exactly what you’re using in each drop. Available percentages and concentrations In addition to composition, CBD oils are also distinguished by their concentration. This value, which is usually expressed

Cannabinoids, Blog

What is CBDP?

We’ve all heard of CBD and THC, but recent research on cannabinoids has revealed that cannabis contains a diversity of molecules that we’re only just beginning to explore. Among them is CBDP, a phytocannabinoid that has captured the attention of some scientific groups for its rare structure and its yet-to-be-discovered biological potential. In this article, we’ll tell you what’s known so far about it, how it’s different from the CBD you already know, and what kind of research is being done to find out. What is CBDP or cannabidiforol? Although its name is reminiscent of CBD, CBDP or cannabidiophorol is part of a subfamily of cannabinoids known as phoroles, a group recently identified in the cannabis plant and characterized by having a seven-carbon alkyl chain. This variation in its chemical structure is uncommon among natural cannabinoids and is the key to the interest it has aroused. Some believe that compounds with this characteristic have a superior potency, as seems to be the case with THCP, another cannabinoid from the same subfamily. It is considered a natural phytocannabinoid as it has been identified in the cannabis plant. However, it is currently not possible to get CBDP plants in the same way that we get CBD flowers. Cannabidiophorol appears in extremely low amounts naturally, which makes it very difficult to obtain directly. For that reason, the CBDP found on the market today is usually made in laboratory processes from isolated extracts. This is why it is often found as a semi-synthetic cannabinoid, despite existing naturally within the plant. History of the discovery of CBDP Today it is recognized as a natural component of cannabis, but its history began in a laboratory, decades ago. In 1945, the effects of THCP, another cannabinoid with a similar structure, were documented for the first time through a synthetic analogue, i.e. it was created in the laboratory. These first observations paved the way for CBDP to eventually be produced in the laboratory, even before it was known that it existed in the plant. But much later, in 2019, a team managed to detect small amounts of CBDP in a specific strain of cannabis. This finding made it possible to reclassify it as a phytocannabinoid, that is, as a compound naturally produced by the plant. However, its presence is still so scarce that most of what is studied about it comes from synthetic versions. As it is such a scarce cannabinoid, there are still very few studies on it, so its biological profile and characteristics are still in very early stages of research (Haghdoost et al., 2024). How is it different from CBD (on a structural level)? From a basic chemical perspective, the main difference between CBDP and CBD is the length of the aliphatic side chain that is part of its molecular structure. While CBD has a five-carbon chain, CBDP is characterized by having a seven-carbon chain. Why does this matter? Because it has been hypothesized that longer side chains could increase affinity with certain receptors in the body, potentially making them more effective. This idea gained traction from the case of THCP, which appears to have stronger effects and interactions than THC (Haghdoost et al., 2024). From there, many wondered if something similar would happen with CBDP compared to CBD. However, current studies don’t fully support that assumption. The study by Haghdoost et al. (2024), one of the few available studies on this compound, did not find major differences in its potency and even pointed out that CBD could be more effective in certain cases. That’s why, while these structural differences are important, there’s still a lot of research to be done to understand how they translate into actual effects on the body. Differences in the effects of CBDP compared to CBD So, does CBDP behave differently in the body? To understand this, it’s helpful to remember how cannabinoids work in the body. These compounds interact with the endocannabinoid system, a network of receptors that helps regulate key functions such as pain, appetite, mood, or immune response. The best-known receptors are CB1, related to the nervous system, and CB2, which acts mainly on the immune system. Recent studies, such as that of Haghdoost et al. (2024), looked at the interaction of both CBD and CBDP with these receptors. The results showed that both compounds generated fairly mild responses. In CB1, neither produced significant effects. In CB2, CBD showed slightly higher activity. Other receptors such as serotonin and dopamine, associated with functions such as mood or motivation, were also evaluated. There, CBD showed mild activity, while CBDP had almost no behavior. Despite these similarities, an interesting difference was observed in one of the receptors outside of the traditional endocannabinoid system, which opened up a possible line of research that we explore below. CBDP’s potential for pain management One of the most relevant findings of the study was the way CBDP interacted with the mu-opioid receptor (MOR), a key protein in pain mechanisms. This receptor does not belong to the endocannabinoid system, but it is essential in many traditional analgesic therapies. In the study, CBDP showed a different action than CBD: instead of decreasing the activity of the receptor (as CBD does), it seemed to enhance it when there was already another substance acting on it. This suggests that CBDP could act as a positive allosteric modulator. In other words, it doesn’t activate the receptor on its own, but it could help amplify its signal if another compound has already activated it. This type of interaction opens up the possibility that CBDP may contribute, under certain conditions, to enhancing the body’s response to pain. Some people even speculate about how this might support the entourage effect by increasing the efficacy of other cannabinoids. Although this effect was moderate and there is still much to be understood, it represents a valuable starting point for future studies. As always, we recommend that you take these results with a grain of salt, as they are preliminary and need to be

Cannabinoids, Blog

Entourage Effect: How Cannabinoids Interact

When talking about cannabis, we often think of individual compounds such as THC or CBD. However, for years, scientists and professionals in the sector have begun to look beyond isolated ingredients. What happens when the different components of the plant interact with each other? The answer to that question has given rise to an increasingly explored hypothesis: the entourage effect. This concept proposes that the effects of cannabis might not depend solely on a specific cannabinoid, but on the joint action of various compounds such as terpenes, flavonoids, and other secondary cannabinoids. It is an idea that has captured interest both in wellness contexts and in research spaces. In this article, we walk you through to find out what’s been observed, what has been suggested in studies, and why this approach could be key to better understanding the potential of cannabis. The Entourage Effect of Cannabis: An Evolving Hypothesis The entourage effect refers to a possible synergy between the different compounds present in cannabis. Rather than acting separately, these components could influence each other and produce broader effects, different from those that each one would have on its own. This could help explain why two cannabis strains, even with similar levels of THC or CBD, can generate different responses. The difference could be in their complete chemical profile, i.e. in the combination of many compounds working together. For those who approach cannabis from curiosity or personal experience, this concept opens up new questions: Does the aroma have an influence? Does the presence of compounds that are almost not mentioned matter? Does it make sense to prefer products that preserve all the elements of the plant? It is in this type of question that the complexity and possibilities opened up by the entourage effect are observed. Origin of the term in scientific research The concept was introduced by Ben-Shabbat et al. (1998), who were researching the endocannabinoid system of the human body. They observed that some compounds that did not generate clear effects on their own could, on the other hand, enhance the effects of other substances that did interact directly with the body’s receptors. This idea that some elements “accompany” and reinforce others gave rise to the name of the entourage effect. Years later, researcher Ethan Russo (2011) took up the concept and applied it to plant cannabis. His proposal was that cannabinoids and terpenes could have combined effects that modify both the observed benefits and the possible side effects. Some examples he proposed include CBD’s ability to reduce anxiety caused by THC, or the possibility that certain terpenes soften the cognitive impact of THC itself. Which Cannabis Compounds Might Be Involved in the Entourage Effect This section allows us to take a closer look at the various chemical actors that might be involved in the entourage effect. Beyond the most well-known ones such as CBD or THC, there would be a whole network of components that interact in complex ways. Understanding their role could help you make more judicious choices between different cannabis products. Secondary cannabinoids: CBG, CBN, and CBC interacting with THC and CBD Cannabinoids are the most well-known active compounds in cannabis, but there is more variety in this category than is usually mentioned. In addition to THC and CBD, there are others such as CBG (cannabigerol), CBN (cannabinol), and CBC (cannabichromene). These so-called “secondary” cannabinoids are not minor in importance: it has been proposed that they could influence how CBD works or alter the way the overall effect of the product is perceived. Sainz Cort (2024) explains that each plant variety has a different chemotype. This means that the percentages of cannabinoids and other compounds vary naturally, generating unique combinations. It is precisely in this diversity that the key to understanding why the same percentage of CBD produces different effects depending on the variety could be found. Cannabis terpenes and their possible modulating effect Terpenes are the compounds responsible for the characteristic aroma of cannabis, but their function could go beyond smell. Some research has suggested that they may also influence the nervous system, interacting with cannabinoid receptors or modifying the bioavailability of other compounds. For example, myrcene has been associated with feelings of relaxation, limonene with more active moods, and pinene with possible greater mental clarity. Voicu et al. (2019) found that some of these terpenes have an affinity for receptors such as CB2, which are involved in the regulation of the immune system. While these effects are still being studied, the possibility of aroma and effects going hand in hand is one of the reasons terpenes generate so much interest. Flavonoids and Less-Studied Compounds: An Expanding Field To a lesser extent, flavonoids are also present in cannabis. They are natural compounds found in many plants that may have antioxidant or anti-inflammatory properties. Marinotti and Sarill (2020) mention that these elements, although not always considered protagonists, could act as complementary pieces that enrich the overall profile of the product. There is still much to discover about its specific role, but its presence is another part of the natural complexity of cannabis. Possible benefits of the entourage effect in cannabis according to scientific studies Understanding how the entourage effect might work opens new doors to different potential applications of hemp and other cannabis strains. Here are the contexts in which studies have begun to explore their usefulness. Inflammation and the immune system: interaction between terpenes and cannabinoids One of the main focuses of research has been inflammation. The immune system regulates many functions of the body and responds to damage, infection, or imbalances. Some studies have observed that the joint action of cannabinoids such as CBD with specific terpenes could have an impact on inflammatory processes. For example, Voicu et al. (2019) highlighted the role of myrcene and limonene when combined with CBD or THC. In these cases, a modulation of the inflammatory response was observed in experimental models. These early tests are valuable clues for future lines of research. Pain, anxiety, and emotional well-being:

Cannabinoids, Blog

Differences Between CBD and CBG

We’ve all heard of CBD. It is normal that, when talking about cannabinoids, it is cannabidiol that gets all the attention. However, there is a wide variety of compounds in this plant that are also beginning to stand out for their particular characteristics. Among them, CBG, called the “mother cannabinoid,” has attracted attention. Both compounds are derived from cannabis, are non-psychoactive, and have been the subject of scientific studies for their potential effects on well-being. Now, what makes them different? How do they act in the body? And above all, why choose between CBG and CBD (or both)? CBD and CBG: origin, characteristics and evolution Before seeing how each one acts in the body, it is important to understand where they come from and what their journey has been. Although both come from the same plant, their concentrations, functions and presence in available products are very different. What is CBD and why has it gained prominence? Cannabidiol, or CBD, is one of the most studied cannabinoids in the cannabis plant. It is found in higher concentration than other compounds and, unlike THC, does not alter perception or mental state. Its profile has been explored in different contexts for its possible ability to influence the balance of the nervous system, inflammation and rest. This wide presence and versatility of applications have made it an ally of the wellness industry and even a common ingredient in CBD creams, balms or oils. What is CBG and why does it attract attention? Cannabigerol, or CBG, is less well known, but it is key in the biosynthesis of other cannabinoids. Its acidic form (CBGA) is the starting point from which CBD, THC, CBC and other cannabinoids derive, hence it is known as “the mother cannabinoid”. However, since much of the CBGA is converted to these other compounds during plant maturation, CBG is usually found in very low concentrations. Only recently, thanks to advances in cultivation techniques and the development of specific strains, has it been possible to obtain greater quantities. Its possible influence on areas such as digestive health, immune response or neuronal activity has begun to be studied. How CBD and CBG work in the body Both CBD and CBG interact with the endocannabinoid system, a biological network involved in functions such as pain, mood, and inflammatory response. However, they do it in different ways. CBD does not bind directly to CB1 and CB2 receptors, but rather modulates them indirectly. This characteristic gives it some flexibility in how it influences different processes in the body. CBG, on the other hand, has shown a more direct affinity for these receptors. It is considered a partial agonist, which means that it could activate certain mechanisms with greater specificity. This difference has drawn attention in studies that analyze its possible more localized or immediate effect on certain functions (Calapai et al., 2022). Other mechanisms studied: receptors and enzymes Both cannabinoids have also been analyzed for their interaction with other systems in the body. One of them is the TRPV1 receptor, linked to pain perception and temperature. Another is the FAAH enzyme, which regulates levels of anandamide, a natural molecule associated with emotional balance and feelings of relief. These parallel paths allow us to observe that both CBD and CBG could influence similar processes, although through different routes. Properties of CBD and CBG: what has been studied and how they could influence well-being Many of the studies on these cannabinoids have focused on looking at how they might be involved in processes related to inflammation, physical discomfort, or brain function. Although research is still ongoing, there are certain areas where preliminary results have aroused considerable interest. Anti-inflammatory and antioxidant activity: comparison between CBD and CBG CBD has been extensively studied for its possible ability to influence immune system molecules known as cytokines, which are related to the body’s inflammatory responses (Atalay et al., 2019). This property has been explored in relation to joint discomfort or skin problems. On the other hand, CBG has been analyzed in laboratory studies on intestinal inflammation, including conditions such as colitis, where it is observed that it could intervene in how inflammation is regulated (Li et al., 2022). In addition, both compounds have been recognized for their potential as antioxidants. This means that they could help neutralize free radicals, molecules that damage cells and are associated with aging and other cellular alterations (Calapai et al., 2024). Together, these protective actions of both compounds have led to new lines of research into their role in the overall balance of the body. CBD and CBG vs. Pain: Possible Differences in Their Mechanisms As for pain, CBD has been linked to its interaction with a protein called TRPV1, which is part of a system that regulates pain perception and body temperature (Blebea et al., 2024). That is why it has been considered in studies that investigate prolonged discomfort, muscle tension or stiffness in joints. CBG, although less studied, has also shown promising signs. It has been observed that it could interact more directly with specific receptors of the endocannabinoid system, such as those called CB1 and CB2. This interaction could be related to more specific effects on types of pain such as acute or nervous-origin (Li et al., 2022; Calapai et al., 2024). This suggests that each of these compounds could act at specific times or types of discomfort. Neuroprotective potential of CBD and CBG according to current research The effects of CBD and CBG on the nervous system have also been analyzed. In the case of CBD, studies suggest that it could help reduce inflammation in the brain and protect neurons from damage caused by so-called oxidative stress, which is a form of cellular imbalance related to neurodegenerative diseases (Fernández-Ruiz et al., 2013). In the case of CBG, research is underway to determine whether it could play a significant role in protecting neurons and in functions such as memory or concentration. Some studies explore its possible influence on the regulation of the immune system

Benefits, Blog

CBD for Tendonitis: How to Relieve Inflammation

Tendonitis is an inflammation that directly affects the tendons, those tissues that connect muscle to bone. When it appears, the body manifests it with discomfort in certain areas and pain that makes it difficult for you to move as you usually do. Sometimes it gets better with rest, but it can be so uncomfortable that it’s natural to look for quicker solutions so you can go about your day-to-day life. In recent years, the use of CBD for tendonitis has sparked interest as an alternative that could act locally on inflammation. This article explores how it would work, what scientific foundations support its use, and how it could be incorporated into a self-care routine in the form of CBD creams or oils. Tendonitis and its relationship with inflammation Maybe it’s already happened to you: a persistent pain in your shoulder, elbow, or knee, which gets worse every time you repeat a certain movement. That discomfort could be tendonitis. This condition occurs when one of your tendons, which are the tissues that connect muscles to bones, becomes inflamed or irritated. The inflammation caused by tendonitis is usually related to repetitive motions or overload in certain areas of the body. It is common in athletes, but also in people who work long hours in front of the computer, or in those who lift weights frequently. In addition, with age the tendons lose elasticity, which increases the risk of suffering this type of injury. Localized pain, tenderness to touch, or swelling are clear signs that something isn’t right. While rest helps, active compounds that work on inflammation may be even more effective and faster in getting you back to your normal routine and mobility. How CBD works on tendonitis inflammation When something in the body isn’t going well, one of its natural responses may be inflammation. However, when that response gets out of control, it can cause discomfort that is longer or more intense than necessary. That is the case with tendonitis. CBD could help you manage inflammation by interacting with a natural network in your body called the endocannabinoid system that is involved in modulating immune and inflammatory responses. Studies such as that of Atalay et al. (2019) suggest that CBD could help reduce certain inflammatory molecules, known as cytokines, without completely shutting down the body’s defenses. It could also help modulate the actions of the endocannabinoid system indirectly, meaning it does not disrupt the body’s natural processes but can make them less uncomfortable. In addition, the same study noted that it could have antioxidant properties, meaning it could protect affected tissues from wear and tear caused by prolonged inflammatory processes. What Studies Say About CBD and Inflammation In addition to the one we already mentioned, a large number of studies have looked at the possible applications of this anti-inflammatory potential of CBD. From the skin to the sports field. The latter is particularly interesting because, in a study by Rojas-Valverde and Fallas-Campos (2023), it was observed that CBD could promote recovery in athletes after demanding training. This happened thanks to the fact that it supported rest, improved their mobility and, as we have said, supported the reduction in inflammation of the body after physical effort, facilitating their recovery. All of these aspects, as we have already mentioned, influence the uncomfortable feeling of tendonitis, which could indicate that CBD could be effective in cases involving these discomforts. Topical application of CBD: a localized tool One of the most common ways to use CBD in these types of situations is through its direct application to the skin. The study by Palmieri et al. (2019) pointed out that the CB2 receptors with which CBD interacts are also present in skin tissue. This means that it might be possible to apply it directly to the affected areas, such as the neck or a specific joint. You can find it in creams and oils designed to be applied right where you feel the discomfort. Step-by-step guide to applying CBD oils and creams When it comes to relieving areas inflamed by tendonitis, CBD oils offer versatility in how you can use it. Topical uses are very useful to act on the affected area, without affecting the rest of the body. Most oils come ready to apply, but some people choose to combine them with a neutral carrier oil, such as almond or jojoba, if they want to adjust the texture or reduce the concentration. There are also those who prefer to make their own homemade creams using CBD oils as a base, although this requires caution and a deeper knowledge of the ingredients involved. In any case, applying the oil with a gentle circular massage to clean skin, and observing how your body reacts, is usually a safe way to start. Conclusion When tendonitis is present, the movement changes. Sometimes it becomes slower, more tense, more uncomfortable. Applying CBD oil directly to the affected area could help relieve that discomfort without disturbing the rest of your body. It is an easy option to incorporate into your day, without neglecting other care strategies. If you are looking for a product that accompanies your recovery in a localized way, at maionais you can explore different types of oils, with concentrations and formats designed so that you find just what you need. The first step can be as simple as testing it carefully and seeing how your body responds. References Atalay, S., Jarocka-Karpowicz, I., & Skrzydlewska, E. (2019). Antioxidative and Anti-Inflammatory Properties of Cannabidiol. Antioxidants (Basel, Switzerland), 9(1), 21. https://doi.org/10.3390/antiox9010021 Rojas-Valverde, D., & Fallas-Campos, A. (2023). Cannabidiol in sports: insights on how CBD could improve performance and recovery. Frontiers in pharmacology, 14, 1210202. https://doi.org/10.3389/fphar.2023.1210202 Palmieri, B., Laurino, C., & Vadalà, M. (2019). A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars. The Therapeutic Clinic, 170(2), e93–e99. https://doi.org/10.7417/CT.2019.2116

Oil CBD, Blog

CBD Extraction with Olive Oil

Not all CBD extraction methods require complex machinery or rare substances to get good results. For some, what’s in the kitchen and a little patience is enough. Olive oil, which we all know all too well, can also be the basis of a simple process for extracting cannabidiol. Let’s look at the keys that those who use this extraction method take into account in a practical way. Why choose olive oil to extract CBD? The extraction of cannabidiol from the cannabis plant can be done using different solvents, and olive oil represents one of the most natural and safest alternatives. This ingredient, widely used in food and cosmetics, has properties that make it suitable for dissolving fat-soluble compounds such as cannabinoids. Its richness in healthy fats, its stability in moderate heat and its antioxidant profile contribute to preserving the integrity of the final extract. Properties of olive oil as a natural solvent Extra virgin olive oil contains monounsaturated fatty acids that promote the solubility of CBD and other compounds present in cannabis. In addition, its non-toxic nature allows it to be used without the need for complex purification processes. Thanks to its natural antioxidant components, such as vitamin E and polyphenols, the stability of the final product is improved, reducing its oxidation. Comparison with other extraction methods Among the most common methods, ethanol and supercritical CO₂ are frequently employed in industrial settings. The former offers quick extraction, but can carry unwanted substances such as chlorophyll. The latter provides high purity, although it involves expensive equipment and specialized technical expertise. Faced with these options, olive oil stands out for its ease of use and for allowing an artisanal process accessible on a small scale. Advantages of home use and its safety The production of CBD extracts with olive oil does not require complex facilities or handling of hazardous substances. The procedure can be performed with common kitchen utensils, making it a viable alternative for those looking to prepare their own cannabis-derived products in home contexts. Its low risk positions it as a safe method for personal, non-commercial uses. Olive Oil Extraction Methods There are mainly two ways to extract compounds from cannabis using olive oil: hot infusion and cold maceration. Each technique has particular characteristics in terms of efficiency, conservation of compounds and preparation times. Hot infusion: process and benefits Heat infusion consists of heating the oil together with the previously decarboxylated plant matter, favoring the dissolution of cannabinoids. This method allows an active extract to be obtained in a few hours, with an appreciable concentration and good bioavailability. However, temperature control is crucial to prevent the degradation of heat-sensitive terpenes. Cold maceration: a slower but preserving option In contrast, cold maceration is based on leaving cannabis in prolonged contact with the oil at room temperature. Although this method requires several weeks to complete, it has the advantage of preserving the profile of terpenes and other volatile compounds more completely. The final concentration of CBD is usually lower than in hot infusion, but with a more complete spectrum. Hot Extraction Process This procedure makes it possible to obtain a functional extract with a good concentration of CBD, using accessible materials and without specialized equipment. Materials Needed CBD flowers, extra virgin olive oil, oven, pot for double boiler or slow cooker, fine mesh or cheesecloth strainer, and dark glass jars are required for storage. Cannabis preparation: drying and decarboxylation Before starting the infusion, it is necessary to activate the cannabinoids through decarboxylation. To do this, the flowers are crumbled and baked for 30 to 40 minutes at a temperature of between 110 and 120°C, stirring occasionally to ensure even exposure. Recommended mix and proportions After decarboxylation, the CBD flowers are mixed with the oil in a pot. A common ratio is 1:1 (gram of cannabis per milliliter of oil), although it can be adjusted according to the desired concentration. The mixture is heated between 60 and 100°C for 2 to 3 hours, preventing the oil from boiling. Occasional movement favors the transfer of active compounds to the solvent. Filtering and preservation of the extract Once the mixture has cooled, it is filtered using gauze or a fine strainer, eliminating solid waste. The extract is stored in opaque jars, in a cool, dry place. Under these conditions, it can remain stable for several months. Frequently asked questions What is the best temperature to extract CBD with olive oil? Extraction is most effective when a temperature between 60 and 100°C is maintained, allowing cannabinoids to be dissolved without degrading them. Higher temperatures can deteriorate sensitive compounds such as terpenes. How long does the extract last once prepared? If stored properly in a dark jar, away from light and heat, the extract can retain its properties for about six months. Its shelf life can vary depending on oxygen exposure and the initial quality of the oil. Is it possible to increase the concentration of CBD? Yes. A higher ratio of plant matter to volume of oil increases the concentration of cannabinoids. The oil can also be reused in a second infusion with fresh material, although this can affect the flavor and texture profile. Conclusion CBD extraction using olive oil represents an accessible, natural and safe alternative to more complex industrial methods. Its technical simplicity and low risk allow its implementation in domestic contexts, facilitating the production of functional extracts without the need for specialized equipment. Although its concentration is often lower than other methods, this technique retains a profile rich in natural compounds and offers a practical entry point for those who want to explore the artisanal preparation of cannabis derivatives. If you are looking for quality CBD oils, extracted with careful and safe processes, be sure to check out the catalog that Maionais CBD has for you. All Maionais CBD oils go through rigorous processes and analyses that ensure that what reaches you is just what you asked for.

CBD Flowers, Blog

How to remove botrytis from dried buds

Cultivation processes often receive meticulous attention from those who work with hemp, from seed selection to care during flowering. However, once the harvest is over, there are still critical stages that can determine the final state of the flowers: drying and curing. Not only are these moments essential for preserving texture and aroma, but they also represent a time when they need to be taken care of from diseases and silent enemies, such as botrytis. This fungus, also known as gray mold, can develop even after the cbd buds have been harvested and stored. The presence of internal humidity, combined with unsuitable environmental conditions, can trigger its appearance and ruin the entire crop. Understanding how to eliminate botrytis in dried buds requires a thorough understanding of its causes, its signs, and the strategies that allow it to be controlled before it compromises an entire harvest. Below, we’ll look at the aspects that growers take into account to prevent this common threat in their CBD flower crops. What is botrytis and how does it affect dried buds? Botrytis, commonly known as gray mold, is one of the most persistent silent enemies in the world of hemp cultivation. This pathogenic fungus has the ability to appear at different times of the process, from flowering to even after drying, when everything seems to be under control. In the case of already dried buds, their presence can be especially frustrating, as it affects flowers that had apparently passed all the critical stages of cultivation. The development of gray mold on dried flowers not only has aesthetic implications, but also compromises their integrity. Grayish spots, loss of firmness, and a musty odor are some of the most obvious indicators. According to recent scientific observations, this fungus does not need much to activate: it is enough for certain internal conditions to be generated within the bud for it to find a favorable environment and begin its expansion (Buirs et al., 2025). Characteristics of gray mold Botrytis cinerea is an opportunistic fungus. This means that it can lie dormant for days or weeks, giving no sign of its presence, until it detects enough moisture and heat to start growing. In studies on greenhouse cultivation, it has been observed that the most critical days for its appearance are between the fifth and sixth week of flowering. During this period, the inside of the buds usually registers higher temperatures and humidity levels than the general environment, thus favoring their appearance. Infected flowers lose their firmness, acquire a soft or brittle texture, and in some cases may show a thin, cottony layer of gray. This aspect is not only a visual issue: botrytis directly alters the structure of the flower, weakening its tissues and reducing its ability to preserve. Conditions that favor their appearance The appearance of botrytis does not occur randomly. There are a series of environmental and physical conditions that, when they coincide, create the perfect scenario for its development. The first key factor is residual moisture. Even if the drying appears complete on the surface, the inside of the flowers can still retain water, especially in particularly dense varieties. In fact, it has been recorded that the relative humidity inside the bud can be up to 15% higher than in the outdoor environment, and the internal temperature can increase 2.5°C above that of the greenhouse. This hot, humid microclimate is not easy to spot with the naked eye, but it creates a stable environment for botrytis spores to activate. Poor ventilation also plays an important role in this process. In spaces where air does not circulate fluidly, pockets of moisture form that, when trapped between the buds, serve as a starting point for infection. These situations are usually exacerbated during the summer and early autumn months, when outdoor conditions tend to be milder and wetter. That is why environmental control is essential during all moments of the process, even in the post-harvest stage. Small variations in humidity and temperature can trigger major problems if not identified in time. Common mistakes that increase risk The appearance of botrytis in dried buds is not always due to external causes. In many cases, certain errors during the handling and conservation of flowers can favor their appearance, even when the cultivation has been successful up to that point. This section discusses some of the practices that, although common, can generate conditions that activate the presence of the fungus. Improper or accelerated drying The drying process is a delicate stage that requires patience and control. When flowers are exposed to excessive heat or overly aggressive ventilation, the outer surface can dry out quickly, giving a false sense that the process is over. However, the inside of the bud can still retain moisture, and that internal difference becomes a risk factor. Over time, that trapped moisture can promote fungal formation, even weeks after drying. In addition, hasty drying can damage the flower’s natural aromatic and volatile compounds, reducing its integrity both in terms of preservation and quality. Failure to trim or cure Manicuring, i.e. the removal of small leaves around the bud, also influences the development of botrytis. If it is done very superficially, plant remains may remain that store moisture. On the other hand, if it is done too aggressively, the flower is directly exposed, facilitating its dehydration and weakening its structure. During curing, airtight storage without proper regular ventilation can cause moisture released by the bud to be trapped. This internal condensation generates the exact environment that botrytis needs to activate. That is why controlled aeration during the first few weeks is so important: it prevents unbalanced internal conditions from forming and protects the flower from possible infections. How to detect botrytis in dried buds One of the biggest difficulties associated with botrytis in dried flowers is that it is not always detected immediately. In the initial stages, the signs are discreet and can be mistaken for normal variations in appearance. The change in texture is usually one of the

CBD Flowers, Blog

Dried brown buds

Under certain conditions, even the best-preserved flowers can show unexpected signs of decay. Sometimes, what starts as a small change in the color or texture of the buttons turns out to reveal a deeper problem. What factors cause a CBD flower to turn brown? What can it mean? The brown, dry appearance that sometimes appears is not a simple aesthetic issue. In this article, we explore how the environment, harvesting processes, and certain diseases affect bud health, and what measures growers use to help preserve their optimal state. Why do some buds turn brown and dry? The transformation of fresh, compact buds into brown, brittle structures can be a cause for concern, considering that in hemp, visual and structural quality is a key indicator of good conservation. Although certain varieties are naturally darker in color, the unwanted change to a dull brown hue, accompanied by stiffness or brittleness, is often associated with problems. Understanding which processes are involved in this degradation is the first step to keeping flowers healthy and preserving their characteristics. Environmental Factors: Humidity, Temperature and Ventilation In any growing space, environmental conditions act as fundamental pillars that support the vitality of flowers. When humidity levels are high and ventilation is poor, the environment becomes conducive to fungal growth. On the contrary, very dry environments cause the buds to dehydrate quickly, losing their elasticity and becoming fragile. Temperature also has a significant influence. Excessive heat accelerates the loss of water and volatile compounds that contribute to the natural consistency of flowers. On the other hand, cold temperatures during flowering can slow down the overall development of the plant. Together, these factors are the key that will determine the appearance, texture, structure, and overall quality of the buds. Common mistakes in drying and cutting Once the harvest is finished, the next challenge is drying, a delicate process that directly influences the appearance and preservation of the flowers. If done in improper conditions, with excessive ventilation or high heat, buds can dry unevenly. This generates a hard surface while the interior retains moisture, which favors the appearance of mold as the days go by. Cutting, i.e. the removal of small leaves around the flowers, also has important implications. If done superficially, plant debris may remain that retain moisture or make it difficult to cure evenly. At the other extreme, excessive cutting can leave the buds too exposed, facilitating premature dehydration. The key is to find a balance that ensures good presentation and proper storage. Diseases and pests that affect appearance The health of flowers can also be affected by biological factors, such as fungi and insects, which alter their color, texture, and structure. Early identification of these threats makes it possible to take effective action before irreversible damage occurs. Botrytis: Grey mould on the buds Botrytis, also known as grey mould, often affects buds during the final stage of cultivation, especially when humidity and ventilation conditions are not well controlled. This fungus can develop silently, with no visible signs, until flowering progresses and the microclimate inside the bud becomes warmer and more humid. According to a recent study carried out in greenhouses, the most critical moments for its appearance coincide with advanced flowering stages. During this period, the humidity and temperature inside the buds exceed those in the environment, creating the perfect environment for the disease to become active (Buirs et al., 2025). The constant movement of the air and the choice of less dense varieties for the months or wetter spaces are key factors that help to reduce its impact. Other fungal infections: powdery mildew and Fusarium In addition to gray rot, there are other fungi that directly affect the quality of the buds. Powdery mildew usually manifests as a white, powdery coating on leaves and flowers. Although it may seem harmless at first, this layer blocks the process of photosynthesis, gradually weakening the plant and affecting the overall health of the flowers. Fusarium, on the other hand, acts more invisibly. It attacks the roots and stems, causing a kind of progressive wilting. Often, affected plants appear to drooping for no apparent reason until the root system is checked. This infection is also linked to conditions of excessive humidity and poorly aerated substrates. Preventing their appearance involves paying attention to drainage and maintaining controlled conditions at the base of the crop. Common pests: mites and thrips Small insects can also cause buds that appear dry, damaged, or discolored. Among the most common are mites and thrips, which feed on plant sap, leaving small spots, discolorations or fine cobwebs on leaves and flowers. When these pests attack the buds, they not only alter their appearance, but also weaken the overall structure of the flower, making it more susceptible to dehydration. Some natural methods of control include introducing beneficial insects, using potassium soap, and regularly cleaning the environment. Maintaining a clean and well-managed environment often makes all the difference in preventing this type of damage. Prevention strategies to maintain quality Throughout the entire process, from the vegetative stage to harvest, maintaining stable conditions is essential to preserve the integrity of the flowers. During the warmer months, especially in summer and early fall, plants can become more susceptible to deterioration, particularly those varieties with very dense or closed flowers. Avoiding extreme levels of humidity, strengthening ventilation in the growing space and opting for less compact genetics are decisions that can make a big difference in this critical period. The mid-flowering stages have also been observed to represent a window of increased risk, so it’s helpful to implement preventative measures before the plant reaches that point. The use of fans or exhaust systems helps maintain a steady flow of air, which prevents the formation of humid microclimates where pathogens can thrive. Likewise, avoiding waterlogging when watering and opting for substrates with good drainage improves the overall condition of the roots and, by extension, the entire plant. In addition, regular monitoring helps to detect possible imbalances in a timely manner. Through this preventive

CBD Flowers, Blog

Dried leaves on buds: causes and prevention

Dry leaves around buds can be a sign of a variety of internal or external factors that alter the structural health of the flower. Although in some cases it is a natural process during advanced stages of flowering, its excessive or anticipated presence is often linked to imbalances in the growing environment. For growers, understanding the possible causes behind this phenomenon and how to prevent it can make all the difference in the final development of CBD flowers. Irrigation and nutrients in hemp crops In this section we address two of the most determining factors for the hydration and nutrition of flowers: watering and the use of fertilizers. When not properly managed, they can trigger visible signs such as drying leaves, starting with the areas near the bud. Underwatering or overwatering of the roots One of the most frequent triggers of premature drying of leaves is improper irrigation management. When the substrate remains dry for prolonged periods, water stress occurs, which disrupts essential processes such as photosynthesis. As a result, the leaves near the bud may lose firmness, have brittle edges or take on a brown colour. This dryness not only affects the visual appearance, but also compromises temperature regulation and the overall health of the plant. On the contrary, an excess of irrigation can lead to anaerobic conditions, that is, a lack of oxygen in the root zone. This situation hinders the absorption of nutrients, generating symptoms such as yellowing, leaf weakness and, over time, progressive drying of the foliage. Looking at the weight of the pot, the texture of the substrate, and the rate of absorption can offer clues as to whether watering is being balanced. Excess fertilizers and buildup in the substrate Another relevant factor is the excessive use of fertilizers. The overload of nitrogen, phosphorus or potassium, especially in sensitive phases of flower development, generates accumulations of salts in the substrate. This saturation prevents a balanced assimilation of minerals, which produces what is commonly called “nutrient burn”: a progressive necrosis that begins at the tips and edges of the leaves. This type of damage is usually first seen as a change in color, going from a deep green to a yellowish or brown hue. The affected tissue then dries out and becomes brittle. To avoid this, many people dedicated to cultivation choose to apply fertilizers in moderate doses, slightly below what is recommended by the manufacturers, especially in soils that have already been previously enriched. Environmental stress in hemp flowers In addition to water and nutritional management, environmental conditions can also directly affect the vitality of flowers and the appearance of nearby leaves. Two common factors are explored here: climate (temperature and humidity) and light exposure. Temperatures and humidity outside the recommended range Environmental conditions directly influence the appearance of dry leaves. Excessively high temperatures, coupled with too low humidity levels, often accelerate the dehydration of plant tissue. In these scenarios, leaf transpiration increases, depleting their water reserves more quickly and causing a visible loss of turgor. For example, in indoor spaces without climate control, an unexpected increase in temperature can generate a dry environment that forces the plant to release more water to stay cool. If this process is not compensated by adequate relative humidity, the leaves begin to deteriorate. This loss of water balance is especially visible in the leaves that surround the buds, due to their more exposed position. Excessive direct light on flowers or buds In addition to temperature and humidity, light intensity can have a direct impact on the most delicate leaves. Prolonged exposure to intense light sources, both indoors and outdoors, can cause what is known as light stress. The leaves that protect the buds, especially in the upper areas of the plant, tend to dry out when exposed unprotected at peak radiation hours or when the lamps are poorly positioned. This type of damage can be prevented by adjusting the distance between the lamps and the plant canopy in indoor systems, or by providing partial shade during the hours of strongest sun outdoors. This prevents burns from too much light and protects the structure of the flower. Pests and fungi that damage buds The growing environment can not only be altered by physical variables, but also by biological agents. Pests and fungal infections pose common threats that can manifest themselves in the form of dry or damaged leaves, affecting both their appearance and health. Visible signs on affected leaves and flowers The presence of insects or fungal diseases is directly related to the abnormal drying of the leaves. For example, mites such as spider mites affect the plant’s ability to transport water and nutrients evenly. Its damage manifests itself in the form of light spots that quickly turn brown and brittle. These signs usually appear first on the underside of the leaves and, if not controlled in time, can spread to areas near the bud. Another common case is that of mildew, a fungus that compromises the health of the foliage by covering the leaves with a whitish coating that prevents them from breathing properly. When this happens near the flowers, the impact is greater, as it interferes with the formation and density of the buds. Control and prevention with frequent monitoring In the face of this type of threat, the essential thing is to implement regular controls. Detailed observation of foliage with tools such as magnifying glasses and early detection of spots, fine cobwebs, or strange dusts can be the key to preventing worse conditions. In addition, many people use biological or preventive treatments with specialized products or even with other beneficial organisms. Maintaining the cleanliness of tools, avoiding contact between affected and healthy specimens, and ensuring constant ventilation are also part of the strategies to reduce the risk of infestations and fungal outbreaks. What to do if there are already dry leaves on the buds When leaf drying has already manifested, it is still possible to intervene to limit the damage and promote the recovery of

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